Complex or salt of a platinum (II) compound and a nitrogen conta

Details Complex or salt of a platinum (II) compound and a nitrogen conta Complex or salt of a platinum (II) compound and a nitrogen conta

1978-11-09

1981-07-14

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424245, 424287, A61K 3174, A61K 31555, A61K 3128

Patent

active

042786606

ABSTRACT:
A cis- complex or -salt of a square planar platinum compound and a nitrogen containing oligomer or polymer prepared by reacting a platinum (II) compound with a nitrogen containing oligomer or polymer in an organic solvent or an acidic aqueous medium, said complex or salt being useful for treating animal malignant tumor cells sensitive to cis-square planar platinum compounds.

REFERENCES:
patent: 3892790 (1975-07-01), Tobe et al.
patent: 3904663 (1975-09-01), Tobe et al.
American Druggist, p. 33, 1969.
Leh et al., J. of Pharmaceutical Sciences, 65(3), 315-328, (1976).
Meischen et al., J. Natl. Cancer Inst. 57(4), 841-845, (1976).
Belluco, Organometallic and Coordination Chemistry of Pt., Academic Press, N. Y. 547-548, (1974).

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