Complex or salt of a platinum (II) compound and a nitrogen conta

Details Complex or salt of a platinum (II) compound and a nitrogen conta Complex or salt of a platinum (II) compound and a nitrogen conta

1977-05-02

1979-04-24

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424287, 526 17, 526 23, 526 481, 526241, 528395, C07F 1500

Patent

active

041511859

ABSTRACT:
A cis- complex or -salt of a square planar platinum compound and a nitrogen containing oligomer or polymer prepared by reacting a platinum (II) compound with a nitrogen containing oligomer or polymer in an organic solvent or an acidic aqueous medium, said complex or salt being useful as an anti-cancer agent.

REFERENCES:
patent: 2858306 (1958-10-01), Ratz et al.
patent: 3563918 (1971-02-01), Murch et al.
patent: 3892790 (1975-07-01), Tobe et al.
patent: 3904663 (1975-09-01), Tobe et al.
American Druggist, p. 33, 1969.
Leh et al, J. of Pharmaceutical Sciences, 65 (3), pp. 315-328, (1976).
Meischen et al, J. Natl. Cancer Inst., 57 (4), pp. 841-845, (1976).
Belluco, Organometallic Organometallic and Coordination Chemistry of Pt. Academic Press, N. Y., pp. 547-548, (1974).

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