Complex of Hepatitis B virus polymerase with p11 and method...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S005000

Reexamination Certificate

active

07148013

ABSTRACT:
Disclosed is a complex of the 11 kDa Ca2+binding protein of 11 and Hepatitis B virus polymerase (HBVPol) which moves to Promyelocytic Leukemia Nuclear Body (PMLNB). Furthermore, the present invention discloses a method for controlling movement of the HBVPol/p11 complex into the nucleus of HepG2 cell with adjusting of intracellular Ca2+ion concentration by administrating an agent for controlling calcium ion concentration in HepG2 cells.

REFERENCES:
patent: 2002/0045191 (2002-04-01), Schneider et al.
Bouchard, M.J. “Activation of Inhibition Cellular Calcium and Tyrosine Kinase Signaling Pathways Identify Targets of the HBx Protein Involved in Hepatitis B Virus Replication” J. Virol. (Jul. 2003) 77, 14, 7713-7719.
Science vol. 294, Dec. 14, 2001, pp. 2376-2378 “Calcium Signaling by HBx Protein in Hepatitis B Virus DNA Replication” by Michael J. Bouchard, Li-Hua Wang and Robert J. Schneider.
The EMBO Journal vol. 16 No. 1 pp. 59-68, 1997 “Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids” by Jianming Hu, David O. Toft and Christoph Seeger.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Complex of Hepatitis B virus polymerase with p11 and method... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Complex of Hepatitis B virus polymerase with p11 and method..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complex of Hepatitis B virus polymerase with p11 and method... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3656108

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.