Complex of biologically active protein with reactive high polyme

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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514 6, 514 21, 514802, 514836, 260112R, 260112B, C08G 6948, C08G 6910, C08G 6942

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active

045566895

ABSTRACT:
A protein-polysuccinimide complex wherein a biologically active protein is combined with a polysuccinimide having a mean molecular weight of 2,000 to 1,000,000 and consisting of constitutive units represented by the following formulae: ##STR1## Said complex can be labelled with a radio-metal and can be used as a radioactive diagnostic in the field of nuclear medicine.

REFERENCES:
patent: 3927204 (1975-12-01), Neri et al.
patent: 4385169 (1983-05-01), Kato et al.
Neri et al., "Synthesis of .alpha.,.beta.- Poly[(2-Hydroxyethyl)-DL-Aspartamide], a New Plasma Extender", Jour. Med. Chem., 1973, vol. 16, No. 8, pp.893-897.

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