Complement-fixing monoclonal antibody to human T cells, and meth

Details Complement-fixing monoclonal antibody to human T cells, and meth Complement-fixing monoclonal antibody to human T cells, and meth

1979-04-26

1982-11-30

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 424 8, 424 12, 424101, 424177, 435 7, 435172, 435240, 435241, C12Q 100, G01N 3348, G01N 3368, G01N 3396, A61K 39395, C12N 500, C12N 502, C12N 1500

Patent

active

043615490

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on all normal human T cells and cutaneous T lymphoma cells. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8Ul myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

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