Complement-fixing monoclonal antibody to human T cells

Details Complement-fixing monoclonal antibody to human T cells Complement-fixing monoclonal antibody to human T cells

1984-08-10

1987-04-14

Hazel, Blondel

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

424 85, 4351722, C07K 1500, A61K 39395

Patent

active

046580190

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on all normal human T cells and cutaneous T lymphoma cells. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

REFERENCES:
patent: 4172124 (1979-10-01), Koprowski et al.
patent: 4196265 (1980-04-01), Koprowski et al.
patent: 4284412 (1981-09-01), Hansen et al.

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