Competitive progesterone antagonist for demand-oriented female b

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514579, 514843, A61K 31435, A61K 3113

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active

061437549

ABSTRACT:
This invention describes the novel use of dissociated competitive progesterone antagonists for the production of a pharmaceutical agent for demand-oriented female birth control (pill on demand), which can be used regardless of the point in the menstrual cycle, in a dosage unit that is to be administered on a one-time basis, whose dosage is below the ovulation-inhibiting dosage.

REFERENCES:
patent: 5439913 (1995-08-01), Chwalisz et al.
Experimental and Clinical Endocrinology, vol. 81, No. 2, 1983, pp. 122-136, Strecke, J. et al.
Journal of Steroid Biochemistry, vol. 11, No. 1C, 1979, pp. 963-969, Csapo, A.I. et al.
The New England Journal of Medicine, vol. 316, No. 4, 1987, pp. 187-191, Nieman, L.K. et al.
Human Reproduction, vol. 9, No. 2, Jun. 1994, pp. 11-21, Lebeau, M.C. et al.
European Journal of Obstetrics, Gynaecology and Reproductive Biology, vol. 4, No. 5, 1975, pp. 161-166, Baulieu, E.E.
International Search Report for PCT/EP95/04191 mailed Mar. 22, 1996.

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