Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1990-07-30
1999-07-27
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
436537, 436546, 935 78, C12Q 168
Patent
active
059288620
ABSTRACT:
Methods and compositions for performing assays for target polynucleotide strands include contacting a sample with a reagent which includes a first and a second polynucleotide probe. The first and second probes are capable of assuming a first position wherein the probes are bound to each other and a second position wherein the probes are bound to a target. The probes include label moieties capable of interacting to produce a signal indicative of the probes being in one of the two positions.
REFERENCES:
patent: 4562159 (1985-12-01), Shafritz
patent: 4568649 (1986-02-01), Bertoglio-Matte
Amoco Corporation
Murray William E.
Nucker Christine M.
Scheiner Laurie
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