Competent bacteria

Details Competent bacteria Competent bacteria

2007-12-04

2007-12-04

Vogel, Nancy T. (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S252330

Reexamination Certificate

active

10655914

ABSTRACT:
The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation competence. SpecificE. colistrains, having significantly reduced genome sizes, are disclosed which are highly transformation competent. A medium and methodology is taught which enables transformation efficiencies to be increased further.

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