Compartmentalized dosage form

Details Compartmentalized dosage form Compartmentalized dosage form

2006-10-24

2006-10-24

Tran, S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S453000, C424S454000, C424S463000

Reexamination Certificate

active

07125561

ABSTRACT:
The present invention provides provide a dosage form that prevents misuse of the medicament contained within. The dosage form contains an inactivating substance in combination with the medicament, wherein the two substances are separated by a permeable or semi-permeable partition. The partition becomes impermeable upon activation by a medical professional, thereby effectively sequestering the inactivating substance from the medicament and allowing for the intended administration of the medicament to the patient. Unless activated, however, the inactivating substance and medicament remain commingled in the dosage form, and any attempt to dispense the medicament before activation will result in the release of inactivated medicament.

REFERENCES:
patent: 5866164 (1999-02-01), Kuczynski et al.
patent: 6228863 (2001-05-01), Palermo et al.
patent: 6277384 (2001-08-01), Kaiko et al.
patent: 6865444 (2005-03-01), Howard
patent: 2004/0241218 (2004-12-01), Tavares et al.
patent: 2005/0163856 (2005-07-01), Maloney et al.
Derwent abstract No. DE 2133122 A, Jul. 22, 1976, Daiichi Seiyaku Co., “Multi-Layer Tablets with Controlled Stepwise Release.”

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