Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2002-05-07
2010-10-05
Zhou, Shubo (Joe) (Department: 1631)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C702S020000, C703S011000, C435S006120
Reexamination Certificate
active
07809509
ABSTRACT:
A method for assembling nucleic acid sequence fragments is disclosed. The fragments are assembled using information about their relative position inferred by comparison of the fragments against a known sequence of a related nucleic acid (FIG.3). Additionally, the method localizes fragments to bacterial artificial chromosomes (FIG.1) and determines relative position of bacterial artificial chromosomes using sequence comparison information (FIG.6). The method utilizes the information about relative orientation, mutual distance, fragment localization to bacterial artificial chromosomes, and relative position of bacterial artificial chromosomes to constrain the assembly process (FIG.5), thus resulting in a more accurate assembly requiring fewer sequencing reactions.
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IP Genesis, Inc.
Milosavljevic Aleksandar
Zhou Shubo (Joe)
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