Commercial production of insulin and insulin-like proteins...

Details Commercial production of insulin and insulin-like proteins... Commercial production of insulin and insulin-like proteins...

2003-03-07

2008-07-01

Ibrahim, Medina A (Department: 1638)

Multicellular living organisms and unmodified parts thereof and

Method of introducing a polynucleotide molecule into or...

Nonplant protein is expressed from the polynucleotide

C800S278000, C800S287000, C800S298000, C800S320100, C435S069100, C435S412000

Reexamination Certificate

active

07393998

ABSTRACT:
Plants are engineered to express proinsulin or insulin. The plants can be used as a source of the protein for a variety of purposes. Plant tissue can be orally administered to animals to replace the necessity of injection of insulin. Alternatively, the protein can be extracted from plant tissue and delivered to animals. Plant produced proteins can also provide a less expensive and more readily available source of the protein as reagents or in other experimentation involving insulin proteins.

REFERENCES:
patent: 6096547 (2000-08-01), Goodman et al.
patent: 6642437 (2003-11-01), Lemaux et al.
patent: 2005/0039235 (2005-02-01), Moloney et al.
patent: 1295129 (2001-05-01), None
patent: 0437320 (1991-07-01), None
patent: WO 9821348 (1998-05-01), None
patent: WO 99/16890 (1999-04-01), None
patent: WO 9954452 (1999-10-01), None
Hong, et. al. EP 0437320, Recombinant DNA and its use in producing human insulin, published Jul. 17, 1991.(Applicant's IDS).
Hooker et al, WO 98/21348, Method of Producing Human Growth Factors from Whole Plants or Plant cell cultures, published May 22, 1998. (Applicant's IDS).
Molecular Cell Biology, Lodish et al, 3rdedition, 1995, Scientific American Books, New York, p. 97, Figure 3-41.
Takeshi Arakawa, et al. A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes. Nature Biotechnology vol. 16 Oct 1998.
S,-W. Ma, et al, Transgenic plant expressing autoantigens fed to mice to induce oral immune tolerance. Nature Medicine. vol. 3. No. 7. Jul. 1997.
J. A. Galloway and R. E. Chance. Improving Insulin Therapy: Achievements and Challenges. Horm. Metab. Res. 26 (1994) 591-598.

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