Commercial production of insulin and insulin-like protein in...

Details Commercial production of insulin and insulin-like protein in... Commercial production of insulin and insulin-like protein in...

2008-05-22

2009-06-30

Ibrahim, Medina A (Department: 1638)

Multicellular living organisms and unmodified parts thereof and

Method of introducing a polynucleotide molecule into or...

The polynucleotide contains a tissue, organ, or cell...

C800S278000, C800S298000, C800S295000, C800S320000, C435S069100

Reexamination Certificate

active

07554006

ABSTRACT:
The invention relates to production of proinsulin or insulin in seeds of monocot plants by transformation of monocot plants with a nucleotide sequence encoding proinsulin or insulin under the control of a seed specific promoter.

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patent: WO 9954452 (1999-10-01), None
Arakawa et al. A plant-based cholera toxin B subunit-insulin protein protects the development of autoimmune diabetes. Nature Biotechnology vol. 16, Oct. 1998.
Ma et al., Transgenic plant expressing autoantigens fed to mice to induce oral immune tolerance. Nature Medicine vol. 3, No. 7, Jul. 1997.
Galloway et al. Improving Insulin Therapy; achievements and challenges. Horm. Metab. Res. 26 (1994) 591-598.
Lodish et al., Molecular Cell Biology, 3rd Edition, 1995, Scientific American Books, New York, p. 97, figure 3-41.

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