Combined vaccine compositions

Details Combined vaccine compositions Combined vaccine compositions

2005-08-23

2005-08-23

Housel, James (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Combination of antigens from multiple bacterial species

C424S231100, C424S226100, C424S225100, C424S229100, C424S227100, C424S186100, C424S189100, C424S279100, C424S283100, C530S826000

Reexamination Certificate

active

06932972

ABSTRACT:
Novel combined vaccine composition preferentially for administration to adolescents are provided, comprising a hepatitis B viral antigen and a herpes simplex viral antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, an HPV antigen, a V2V antigen, a HCMV antigen, aToxoplasma gondiiantigen. The vaccine compositions are formulated with an adjuvant which is a preferential stimulator of TH1 cell response such as 3D-MPL and QS21.

REFERENCES:
patent: 0 339 667 (1989-04-01), None
patent: 0 510 996 (1992-04-01), None
patent: WO 92/11291 (1992-07-01), None
Stanberry et al.N. Eng. J. Med. 2002, vol. 347, No. 21, pp. 1652-1661.
Constantin et al. Immunotolerance inTexbook of Immunology, 1990, Edited Constantin et al. pp. 170-174.
Constantin et al. Negative regulation: suppression in Texbook of Immunology, 1990, Edited by Conatantin et al. pp. 255&260.

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