Combined vaccine

Drug – bio-affecting and body treating compositions – Lymphokine

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424 88, A61K 3917, A61K 39235

Patent

active

045377685

ABSTRACT:
Combined, inactivated vaccine ready for administration and active against at least Newcastle disease and egg production drop caused by adeno-like viruses and process for the preparation of such vaccine by addition of (A) a Newcastle disease virus (NDV) containing liquid obtained by cultivation of a NDV, followed by inactivation of the liquid and optionally homogenizing it, together with (B) an adeno-like virus (ALV) containing liquid obtained by cultivation of an ALV, followed by inactivation of the liquid and optionally homogenizing it, to an oil phase containing as essential components at least one of the components selected from the group consisting of light paraffinic mineral oils, vegetable oils and naphtenic mineral oils and one or more emulsifiers such as nonionic surface-active compounds derived from alkylene oxide and/or hexahydric alcohols and/or higher natural fatty acids such as esters or ester-ethers, optionally followed by homogenizing and/or addition of a preservative.

REFERENCES:
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patent: 3083142 (1963-03-01), Howell et al.
patent: 3149036 (1964-09-01), Woodhour et al.
patent: 3399263 (1968-08-01), Strazdins et al.
patent: 3678149 (1972-07-01), Prigal
patent: 3755557 (1973-08-01), Jacobs
patent: 3876763 (1975-04-01), Yoshikazu et al.
patent: 3906092 (1975-09-01), Hilleman et al.
patent: 3983228 (1976-09-01), Woodhour et al.
patent: 4069313 (1978-01-01), Woodhour et al.
patent: 4073743 (1978-02-01), Midler et al.
Veterinary Bulletin 47, #1481, #6897 (1977), 48, #2966, #2971 , #4417, #5414, #5417, #5421, #7257 (1978).

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