Combined perfusion and oxygenation organ preservation apparatus

Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or... – Including perfusion; composition therefor

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435283, 435289, 261 35, 2611221, A01N 102

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active

053567714

ABSTRACT:
A method and apparatus is provided for long-term extracorporeal preservation of living tissue. A tissue preservation device including a gas permeable membrane and perfusate allows oxygenation of the living tissue. The gas permeable membrane allows gas from a cyclically pumped source to permeate and expand the membrane, simultaneously oxygenating the perfusate and pumping the oxygen-enriched perfusate through the tissue. Simply constructed of a few basic components, the tissue preservation device is capable of operating in many physical orientations, and requires no electrical power for operation. Also provided is an apparatus for cooling and transporting the tissue preservation device.

REFERENCES:
patent: 3632473 (1972-01-01), Belzer et al.
patent: 3777507 (1973-12-01), Burton et al.
patent: 3818934 (1974-06-01), Borsanyi
patent: 3843455 (1974-10-01), Bier
patent: 3892628 (1975-07-01), Thorne et al.
patent: 3914954 (1975-10-01), Doerig
patent: 3935065 (1976-01-01), Doerig
patent: 4186565 (1980-02-01), Toledo-Pereyra
patent: 4242883 (1981-01-01), Toledo-Pereyra
patent: 4745759 (1988-05-01), Bauer et al.
patent: 4837390 (1989-06-01), Reneau
patent: 4951482 (1990-08-01), Gilbert
patent: 5051352 (1991-09-01), Martindale et al.
patent: 5141847 (1992-08-01), Sugimachi et al.
patent: 5217860 (1993-06-01), Fahy et al.
M. Yland, et al., "A Homeostatic Perfusion Method and Apparatus: A New Approach to In Vitro Hibernation," manuscript, Depts. of Surgery and Anesthesiology, University Hospital Stony Brook, Stony Brook, N.Y. (undated).
Petsika, et al., "Adenosine Enhances Left Ventricular Flow During 24-Hour Hypothermic Perfusion of Isolated Cardiac Allografts," 9 J. Heart Transpl. pp. 543-547 (1990).
Minten, et al., "Differences in High-Energy Phosphate Catabolism Between the Rat and the Dog in a Heart Preservation Model," 10 J. Heart and Lung Transpl. pp. 71-78 (1991).
Wicomb, et al., "Value of Polyethylene Glycol (PEG) and Horseradish Peroxidase (HRP) for Hypothermic Rabbit Heart Perfusion," 21 Transpl. Proc. pp. 1366-1368 (1989).
Qayumi, et al., "Comparison of Functional and Metabolic Assessments in Preservation Techniques for Heart Transplantation," 4 J. Investigative Surgery pp. 93-102 (1991).

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