Combined heterogeneous specific binding assay

Details Combined heterogeneous specific binding assay Combined heterogeneous specific binding assay

1979-10-29

1982-02-16

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 422 61, 424 12, 435 7, G01N 3356, G01N 3358

Patent

active

043159079

ABSTRACT:
A heterogeneous specific binding assay method and test means for the simultaneous determination of each of a plurality of different ligands (e.g., antibodies, antigens or haptens) in a single liquid test sample. The assay may follow any conventional technique of a heterogeneous type, i.e., which includes a separation of a bound-species from a free-species form of the labeled reagent. The combined assay is accomplished by using solid-phase binding agents for the respective ligands to be determined which are differentially separable from each other, thereby permitting the use of a single label rather than a different label for each ligand to be determined. The assay is particularly suited to the simultaneous determination of different antibodies, particularly antibodies to different viral antigens, in a single serum sample.

REFERENCES:
patent: 4135884 (1979-01-01), Shen
patent: 4207307 (1980-06-01), Kaul et al.

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