Combined estrogen and antiestrogen therapy

Details Combined estrogen and antiestrogen therapy Combined estrogen and antiestrogen therapy

1999-05-06

2000-12-12

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514319, 514410, A61K 3156, A61K 31445, A61K 3140

Patent

active

06159959&

ABSTRACT:
The present invention relates to pharmaceutical compositions containing benzo[a]carbazoles or indenoindoles, which are useful as tissue selective estrogenic agents, having the general structures below: ##STR1## and one or more estrogens and methods of treatment utilizing these formulations.

REFERENCES:
patent: 4656187 (1987-04-01), Black et al.
patent: 4894373 (1990-01-01), Young
patent: 4943572 (1990-07-01), von Angerer
patent: 5023254 (1991-06-01), von Angerer
patent: 5051442 (1991-09-01), Salituro et al.
patent: 5124335 (1992-06-01), Patchett et al.
patent: 5389641 (1995-02-01), Naka et al.
patent: 5395842 (1995-03-01), Labrie et al.
patent: 5496844 (1996-03-01), Inai et al.
patent: 5534527 (1996-07-01), Black et al.
patent: 5550107 (1996-08-01), Labrie
patent: 5552401 (1996-09-01), Cullinan et al.
patent: 5591753 (1997-01-01), Black et al.
patent: 5646137 (1997-07-01), Black et al.
patent: 5672609 (1997-09-01), Bryant et al.
patent: 5852039 (1998-12-01), Sohda et al.
von Angerer et al., J. Med. Chem . . , vol. 33, No. 9, pp. 2635-2640, 1990.
von Angerer et al., J. Med. Chem., vol. 30, No. 1., pp. 132-136, 1987.
Rackeley, Contemporary Treatment in Cardiovascular Disease, 1, pp. 49-58 (1996).
von Angerer et al., Ann. N.Y. Aca. Sci., pp. 176, 177, 189, 1995.
Oparil "Hypertension in postmenopausal Woman:Pathology and Management" EMBASE 95:283951, 1995.
von Angerer et al., J. Med. Chem. vol. 27, pp. 1439-1447, 1984.
Biberger, J. Steroid Biochem. Molec., vol. 58, No. 1, pp. 31-43 (1996).
Bone, vol. 17, No. 4, Oct. 1995, 181S-190S.
Von Angerer, J. Med. Chem. (1983), vol. 26 (1), pp. 113-116.
Kauppila et al., Am. J. Obstet. Gynecol., vol. 140, No. 7, 1981, pp. 787-792.
Kauppila et al., Arch. Gynecol. (1983) 234:49-58.
Segall et al., Eur. J. Med. Chem., 30, No. 2, 165-169 (1995).
Klinicheskaya Farmakologiya i Terapiya, 1996, 5 (1), pp. 70-75.
Klinicheskaya Farmakologiya i Terapiya, 1994, 3 (3), pp. 30-39.

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