Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2008-06-03
2008-06-03
Crouch, Deborah (Department: 1632)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C424S093200, C424S093210
Reexamination Certificate
active
07381710
ABSTRACT:
The present invention relates to the combination of a DNA vaccination strategy that makes use of a nucleic acid encoding an immunogenic polypeptide, with a non-immunosuppressive inducer of tumor cell differentiation and/or apoptosis or a tumor cell modifier, useful for cancer therapy. Vaccine compositions and kits are provided, as well as specific nucleic acid constructs that are particularly suitable for the preparation of such compositions.
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patent: WO 95/04151 (1995-02-01), None
Le et al. Recombinant PML Adenovirus Suppresses Growth and Tumroigenicity of Human Breast Cancer Cells by Inducing G1 Cycle Arrest and Apoptosis. Oncogene. 1998, vol. 16, pp. 1839-1849.
Pandolfi et al. Structure and Origin of the Acute Promyelocytic Leukemia myl/RARAlpha cDNA and Characterization of its Retinoid-Binding and Transactivation Properties. Oncogene. 1991, vol. 6, pp. 1285-1292.
Grignani et al. Acute Promyelocytic Leukemia: From Genetics to Treatment. Blood. 1994, Jan. 1, 1994, pp. 10-25.
Charron Dominique
Chomienne Christine
Padua Rose Ann
Crouch Deborah
Institut National de la Sante et de la Recherche Medicale
Schulman B. Aaron
Stites & Harbison PLLC
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