Combined antiestrogens and antigonadotropically effective antian

Details Combined antiestrogens and antigonadotropically effective antian Combined antiestrogens and antigonadotropically effective antian

1980-10-10

1982-01-12

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A01N 4500, A61K 3156

Patent

active

043105238

ABSTRACT:
A pharmaceutical composition comprising an anti-estrogen and an antigonadotropically effective anti-androgen, e.g., in a weight ratio of anti-estrogen to anti-androgen of essentially 2:1 to 1:10 is effective for the prophylaxis and therapy of prostate hyperplasia. Suitable anti-estrogens include, for example, tamoxifen. Antigonadotropically active anti-androgens preferably are steroids having anti-androgenic and progestational properties, e.g., cyproterone acetate.

REFERENCES:
patent: 3076823 (1963-02-01), Ringold et al.
patent: 3423507 (1969-01-01), Neri
patent: 4055641 (1977-10-01), Benson et al.
Chem. Abstracts (1978), vol. 89, Par. 197804g.

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