Combinatorial synthesis on soluble polyvalent supports having a

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 4, 435 71, 435DIG48, 436501, 436536, 436539, 530338, 536 253, C12Q 100, G01N 3353

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061329533

ABSTRACT:
The present invention is directed to the use of a soluble polyvalent support for the preparation of combinatorial libraries of compounds. The resultant combinatorial libraries are useful in screening for biologically active moieties in the drug discovery process or in developing compounds with desired physical and chemical properties.

REFERENCES:
patent: 5877214 (1999-03-01), Kim
Kim, R.M., et al, Chem. Abstracts, vol. 125:300752 & Proc. Natl. Acad. Sci., vol. 93(19), pp. 10012-10017, 1996.
Kim, R. "Solution-Phase Combinational Chemistry on Dendrimer Supports" in Registration Bulletin for "Randomn & Rational Drug Discover . . . " by Strategic Research Institute to be held Sep. 16-17, 1996.
Coe, D. "The use of Dendrimes as Soluble Supports" Abstract of Presentation at IBC Forum "Combinatgorial Technologies" held Oct. 23-24, 1997.
Mutter, M.; Hagenmaier, H.; Bayer, E., Angew. Chem., Int. Ed. Engl. (1971), vol. 10, 811.
Koster, H., Tetrahedron Lett. (1972), 1535.
Bayer, E.; Mutter, M. Nature (London) 1972, 237, 512.
Schott, H., Angew. Chem., Int. Ed. Engl. (1973), vol. 12, 246.
Andreatta, R.H./Rink, H., Helv. Chim. Acta (1973), vol. 56, 1205.
De Napoli, L.; Messere, A.; Montesarchio, D.; Piccialli, G.; Santacroce, C.; Bonora, G. M. Nucleosides Nucleotides (1993), vol. 12, 21.
Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D., Proc. Natl. Acad. Sci. USA (1995), vol. 92, 6419.
Geckeler, K. E., Adv. Polym. Sci. (1995), vol. 121, 31.
Gravert, D. J.; Janda, K. D.; Chem. Rev. (1997), vol. 97, 489-509.
Seliger, H.; Aumann, G./Tetrahedron Lett. (1973), 2911.

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