Coating processes – Measuring – testing – or indicating
Patent
1994-10-18
1999-11-16
Hamilton, Cynthia
Coating processes
Measuring, testing, or indicating
427265, 427266, 436 79, 436 80, 436157, 436 78, 436 81, 436 82, 436 83, 436 84, 436 73, 436148, 436149, 436170, 436174, 436182, B05D 134, B05D 136, G01N 128, G01N 2100
Patent
active
059853565
ABSTRACT:
Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc. Once prepared, these materials can be screened for useful properties including, for example, electrical, thermal, mechanical, morphological, optical, magnetic, chemical, or other properties. Thus, the present invention provides methods for the parallel synthesis and analysis of novel materials having useful properties.
REFERENCES:
patent: 2981607 (1961-04-01), Danaczko
patent: 3871935 (1975-03-01), Eppler et al.
patent: 4004935 (1977-01-01), Grosvenor et al.
patent: 4468419 (1984-08-01), McBride
patent: 4728502 (1988-03-01), Hamill
patent: 4956335 (1990-09-01), Agostinelli et al.
patent: 5024992 (1991-06-01), Morris
patent: 5034359 (1991-07-01), Fukushima et al.
patent: 5045916 (1991-09-01), Vor et al.
patent: 5120707 (1992-06-01), Maxfield et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5288514 (1994-02-01), Ellman
patent: 5306411 (1994-04-01), Mazanec et al.
patent: 5324483 (1994-06-01), Cody et al.
patent: 5384261 (1995-01-01), Winkler et al.
patent: 5478800 (1995-12-01), Itozaki et al.
Briceno, et al., Science, 270:273-275 (1995).
Jonker, et al., Physica, XIX:120-130 (1953).
Mahendiran, et al., Rev. Sci. Instrum., 66(4):3071-3072 (1995).
Yamaguchi, et al., Journal of the Physical Society of Japan, 64(6):1885-1888 (1995).
Barbas et al. "Assembly of combinatorial antibody libraries on phage surfaces: The gene III site." Proc. Natl. Acad. Sci., vol. 88 (Sep. 1991), pp. 7978-7982.
Blake, James and Litzi-Davis, Leonara. "Evaluation of Peptide Libraries: An Iterative Strategy to Analyze the Reactivity of Peptide Mixtures with Antibodies." Bioconjugate Chem., vol. 3, No. 6 (1992), pp. 510-513.
Bray et al. "The Simultaneous Multiple Production of Solution Phase Peptides; Assessment of the Geysen Method of Simultaneous Peptide Synthesis." Tetrahedron Letters, vol. 31, No. 40 (1990), pp. 5811-5814.
Bunin et al. "The combinatorial synthesis and chemical and biological evaluation of 1,4-benzodiazepine library." Proc. Natl. Acad. Sci. USA, vol. 91, (May 1994), pp. 4708-4712.
Cava, R.J. "Structural Chemistry and the Local Charge Picture of Copper Oxide Supeconductors." Science, vol. 247 (Feb. 9, 1990), pp. 656-662.
Cwirla et al. "Peptides on phage; A vast library of peptides for identifying ligands." Proc. Natl. Acad. Sci., vol. 87 (Aug. 1990), pp. 6378-6382.
Devlin et al. "Random Peptide Libraries: A Source of Specific Protein Binding Molecules." Science, vol. 249 (Jul. 27, 1990), pp. 404-406.
DiSalvo, Francis J. "Solid-State Chemistry: A Rediscovered Chemical Frontier." Science, vol. 247 (Feb. 9, 1990), pp. 649-655.
Ellington, Andrew D. and Szostak, Jack W. "In vitro selection of RNA molecules that bind specific ligands." Nature, vol. 346 (Aug. 30, 1990), pp. 818-822.
Fister et al. "Controlling Solid State Reactions via Rational Design of Superlattice Reactants" in Advances in the Synthesis and Reactivity of Solids (city of publication?), JAI Press Inc., 1994), 155, only).
Fodor et al. "Light-Directed, Spatially Addressable Parallel Chemical Synthesis." Science, vol. 251 (Feb. 15, 1991), pp. 767-773.
Houghton et al. "Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery." Nature, vol. 354 (Nov. 7, 1991), pp. 84-86.
Jin et al. "Thousandfold Change in Resistivity in Magnetoresistive La-Ca-Mn-O Films." Science, vol. 264 (Apr. 15, 1994), pp. 413-415.
Lam et al. "A new type of synthetic peptide library for identifying ligand-binding activity." Nature, vol. 354 (Nov. 7, 1994), pp. 82-84.
Lerner et al. "At the Crossroads of Chemistry and Immunology: Catalytic Antibodies." Science, vol. 242 (May 3, 1991), pp. 659-667.
Maeda et al. "A New High-T.sub.c Oxide Superconductor without a Rare Earth Element." The Journal of Applied Physics, vol. 27, No. 2 (Feb., 1988), pp. L209-L210.
Needels et al. "Generation and screening of an oligonucleotide-encoded synthetic peptide library." Proc. Natl. Acad. Sci. USA, vol. 90 (Nov. 1993), pp. 10700-10704.
Ohlmeyer et al. "Complex synthetic chemical libraries indexed with molecular tags." Proc. Natl. Natl. Acad. Sci. USA, vol. 90 (Dec. 1993), pp. 10922-10926.
Pollack, Scott J. "Selective Chemical Catalysis by an Antibody." Science, vol. 234 (Dec. 19, 1986), pp. 1570-1573.
Scott, Jamie K. and Smith, George P. "Searching for Peptide Ligands with an Epitope Library." Science, vol. 249 (Jul. 27, 1990), pp. 386-390.
Sleight, A.W. "Chemistry of High-Temperature Superconductors." Science, vol. 242 (Dec. 16, 1988), pp. 1519-1527.
Tramontano et al. "Catalytic Antibodies." Science, vol. 234 (Dec. 19, 1986), pp. 1566-1570.
Tuerk, Craig and Gold, Larry. "Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase." Science, vol. 249 (Aug. 3, 1990), pp. 505-510.
Geysen et al. "Strategies for Epitope Analysis Using Peptide Synthesis." Journal of Immunological Methods, 102 (1987), pp. 259-274.
Hor, et al., Superconductivity at 93 K in a New Mixed-Phase Y-Ba-Cu-O-Compound System, Physical Review Letters, vol. 58, No. 9 (Mar. 2, 1987) pp. 908-910.
Hor, et al., "High-Pressure Study of the New Y-Ba-Cu-O-Superconducting Compound System," Physical Review Letters, vol. 58, No. 9 (Mar. 2, 1987) pp. 911-912.
Bednorz, et al., "Possible High Tc Superconductivity in the Ba-La-Cu-O System," Zeitschrift fur Physik B, Condensed Matter 64 (1986) pp. 189-193.
Hanak, "The `Multiple-Sample Concept` in Materials Research: Synthesis, Compositional Analysis and Testing of Entire Multicomponent Systems," Journal of Materials Science, 5:964-971 (1970).
Hanak, "A Step Toward Automation of Materials Research," RCA Technical Report (Apr. 3, 1969).
Berlincourt, "Proposed Search for High-Temperature Superconductors," Research proposal (Aug. 28, 1973).
Hanak, "Electroluminescence in ZnS:Mn.sub.x : Cu.sub.y rf-Sputtered Films," Japan J. Appl. Phys., Suppl. 2, Pt. 1, pp. 809-812 (1974).
Hanak, et al., "Radio-Frequency Sputtered Films of .beta.-Tungsten Structure Compounds," J. Appl. Phys., 41(12):4958-4962 (1970).
Hanak, et al., "The Effect of Grain Size of the Superconducting Transition Temperature of the Transition Metals," Physics Letters, 30A(3):201-202 (1969).
Hanak, et al., "Calculation of composition of dilute cosputtered multicomponent film Systems," J. Appl. Phys., 44(11):5142-5147 (1973).
Hanak, "Compositional Determination of rf Co-Sputtered Multicomponent Systems,"J. Vac. Sci. and Tech., 8(1):172-175 (1971).
DaSilva, et al., "Variable Thim Film Thickness Apparatus," IBM Technical Disclosure Bulletin, 22(7):2922 (1979) Dec.
Goldwasser Isy
Schultz Peter G.
Xiang Xiaodong
Hamilton Cynthia
Symyx Technologies
The Regents of the University of California
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