Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-11-14
1999-10-12
Fonda, Kathleen K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 41, 536 186, 536122, 514 24, C07H 1500
Patent
active
059657197
ABSTRACT:
Disclosed are methods for synthesizing very large collections of diverse thiosaccharide derivatives optionally attached to a solid support. Also disclosed are libraries of diverse thiosaccharide derivatives.
REFERENCES:
patent: 5079353 (1992-01-01), Ratcliffe et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5593853 (1997-01-01), Chen et al.
Hol, W. G. J., et al., "Structure and Function of E. Coli Heat-Labile Enterotoxin and Cholera Toxin B Pentamer", Bacterial Toxins and Virulence Factors in Disease, Ed. by J. Moss et al., Marcel Dekker, Inc. (1995).
Spangler, B. D., "Structure and Function of Cholera Toxin and Related Escherichia coli Heat-Labile Enteroxin", Microbilological Reviews, 56(4):622-647 ( Dec. 1992).
Evans et al., J. Amer. Chem. Soc., 112:4011-4030 (1990).
Williams et al., J. Amer. Soc., 113:9276-9286 (1991).
J. Defaye et al., "Thiooligosaccharides: Their Synthesis and Reactions with Enzymes" in Studies in Natural Products Chemistry, vol. 8, pp. 315-357, Elsevier Science Publishers (1991).
J.M. Kerr, S.C. Banville and R.N. Zuckermann, J. Am. Chem. Soc., 115:2529 (1993).
M.C. Needels, D.G. Jones, E.M. Tate, G.L. Heinkel, L.M. Kochersperger, W.J. Dower, R.W. Barrett and M.A. Gallop, Proc. Natl. Acad. Sci., USA, 90:10700 (Nov. 1993).
M.H.J. Ohlmeyer, R.N. Swanson, L.W. Dillard, J.C. Reader, G. Asouline, R. Kobyashi, M. Wigler and W.C. Still, Proc. Natl. Acad. Sci. USA, 90:10922 (Dec. 1993).
Svennerholm, A-M. et al., Current Microbiology, 1:19-23 (1978).
Witczak, Z. J. et al., Synthesis of L-Fucopyrasnosyl, 4-Thiodisacchasrides from Levoglucosenone and Their Inhibitory Activity on .alpha.-L-Fucosidase, "Bioorganic & Medicinal Chemistry Letters", vol. 5, No. 18:2169-2174, 1995.
Collins et al., "Monosaccharides: Their Chemistry and Their Roles in Natural Products," John Wiley & Sons, Chichester, England, 1995, pp. 97-106.
Ferrier et al., Carbohydrate Chemistry 1996, 28, 158-164.
Ferrier et al., Carboyhdate Chemistry 1993, 27, 140-147.
Williams et al., Carboyhdrate Chemistry 1983, 17, 116-119.
Horton et al., Thio Sugars and Derivatives, In "The Carbohydrates: Chemistry and Biochemistry", 2.sup.nd Edition , Pigman et al., eds. Academic Press, New York, 1980.
Schnabeirauch et al, Helv. Chim. Acta 1994,77, 778.
WPI/Derwent Abstract AN 93-088661, JP 910193287, Aug. 1, 1991.
Fonda Kathleen K.
Sunsorb Biotech, Inc.
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