Combinatorial process for preparing substituted thiophene librar

Details Combinatorial process for preparing substituted thiophene librar Combinatorial process for preparing substituted thiophene librar

1997-08-25

1999-08-24

Marschel, Ardin H.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 6, 435810, 540 1, 549 1, 549 29, 549 62, 549 63, 549 68, 549 78, C12Q 168

Patent

active

059423870

ABSTRACT:
This invention relates to a novel solid phase process for the preparation of thiophene combinatorial libraries. These libraries have use for drug discovery and are used to form wellplate components of novel assay kits.

REFERENCES:
patent: 5712171 (1998-01-01), Zambias et al.
patent: 5736412 (1998-04-01), Zambias et al.
Chemistry of Heterocyclic Compounds Edward C. Taylor, Editor; Thiophene and its Derivatives, Salo Gronowitz, Ed., Chap.IV, "Nitrothiophenes and Their Reactions," Robert Norris, pp. 523-629, John Wiley & Sons, Inc. New York, 1985.
"Nucleophilic Substitution Reactions on Chlorinated Thiophene Derivatives as Basis for the Synthesis of Thienoanellated O,N- and S,N-Heterocyclic", Puschmann, et al., Heterocyclis, vol. 36, No. 6, pp. 1323-1332, 1993.

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