Combinatorial libraries of labeled biochemical compounds and met

Details Combinatorial libraries of labeled biochemical compounds and met Combinatorial libraries of labeled biochemical compounds and met

1996-06-21

1998-04-21

Achutamurthy, Ponnathapura

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436501, 436524, 436528, 436531, 4352571, 530350, 5303871, G01N 33543, C12N 112, C07K 100

Patent

active

057417130

ABSTRACT:
Combinatorial libraries of labeled biochemical compounds and methods for producing such combinatorial libraries comprising the steps of producing labeled individual units, combining at least two of the labeled individual units so as to produce a labeled biochemical compound, and repeating this process at least once so as to produce a combinatorial library of labeled biochemical compounds. Also, methods for determining the conformation of a biochemical compound which comprise producing a combinatorial library of labeled biochemical compounds, contacting the combinatorial library of labeled biochemical compounds with a target receptor molecule so that a selected labeled biochemical compound binds to the target receptor molecule, and determining the conformation of the selected labeled biochemical compound when bound to the receptor molecule.

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