Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1996-10-18
2000-01-25
Achutamurthy, Ponnathapura
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
436524, 436525, 436526, 436527, 436528, 436529, 436530, 436531, G01N 33543
Patent
active
060177683
ABSTRACT:
Combinatorial libraries are disclosed which are represented by Formula I: ##STR1## wherein: ##STR2## is a solid support; T'--L-- is an identifier residue; and --L'--II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of the formula ##STR3## which interact (i.e., as agonists or antagonists) with .alpha. adrenergic receptors, dopamine receptors, .sigma.-opiate receptors, and K.sup.+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatment of ocular diseases such as glaucoma.
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Baldwin John J.
Dillard Lawrence W.
Li Ge
Reader John C.
Zeng Wenguang
Achutamurthy Ponnathapura
Pharmacopeia Inc.
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