Combinatorial artificial receptors including peptide...

Combinatorial chemistry technology: method – library – apparatus – Library – per se – Library containing only organic compounds

Reexamination Certificate

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C506S003000, C506S032000, C435S007100, C514S016700

Reexamination Certificate

active

07985715

ABSTRACT:
The present invention relates to artificial receptors, arrays or microarrays of artificial receptors or candidate artificial receptors, methods of and compositions for making them, and methods of using them. Each artificial receptor includes a building block molecule that is a peptide of Formula:in-line-formulae description="In-line Formulae" end="lead"?R1R2N—R3—(R4)n—X—(R5)m—Y—C(O)—R6,in-line-formulae description="In-line Formulae" end="tail"?in-line-formulae description="In-line Formulae" end="lead"?Tether-R1NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)—R6,in-line-formulae description="In-line Formulae" end="tail"?in-line-formulae description="In-line Formulae" end="lead"?R1R2NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)-Tether,in-line-formulae description="In-line Formulae" end="tail"?in-line-formulae description="In-line Formulae" end="lead"?Linker-R1NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)—R6, orin-line-formulae description="In-line Formulae" end="tail"?in-line-formulae description="In-line Formulae" end="lead"?R1R2NH—Z-Ala-Gly-Ala-Gly-X-Ala-Y—C(O)-Linker.in-line-formulae description="In-line Formulae" end="tail"?

REFERENCES:
patent: 4344438 (1982-08-01), Schultz
patent: 5159656 (1992-10-01), Goldstein
patent: 5178673 (1993-01-01), Caster et al.
patent: 5225374 (1993-07-01), Fare et al.
patent: 5281539 (1994-01-01), Schramm
patent: 5324633 (1994-06-01), Fodor et al.
patent: 5340474 (1994-08-01), Kauvar
patent: 5453533 (1995-09-01), Luo et al.
patent: 5475100 (1995-12-01), Hashino et al.
patent: 5508164 (1996-04-01), Kausch et al.
patent: 5512435 (1996-04-01), Renschler et al.
patent: 5632957 (1997-05-01), Heller et al.
patent: 5677196 (1997-10-01), Herron et al.
patent: 5690894 (1997-11-01), Pinkel et al.
patent: 5770380 (1998-06-01), Hamilton et al.
patent: 5804563 (1998-09-01), Still et al.
patent: 5925529 (1999-07-01), Coughlin et al.
patent: 5942393 (1999-08-01), Nobori et al.
patent: 5990163 (1999-11-01), Evans et al.
patent: 5993653 (1999-11-01), Ahmed et al.
patent: 5998594 (1999-12-01), Goodman et al.
patent: 6030782 (2000-02-01), Anderson et al.
patent: 6030917 (2000-02-01), Weinberg et al.
patent: 6061636 (2000-05-01), Horlbeck
patent: 6066448 (2000-05-01), Wohlstadter et al.
patent: 6083758 (2000-07-01), Imperiali et al.
patent: 6083763 (2000-07-01), Balch
patent: 6096551 (2000-08-01), Barbas et al.
patent: 6111123 (2000-08-01), Coucouvanis et al.
patent: 6153743 (2000-11-01), Hubbell et al.
patent: 6168912 (2001-01-01), Chen
patent: 6207369 (2001-03-01), Wohlstadter et al.
patent: 6225047 (2001-05-01), Hutchens et al.
patent: 6251864 (2001-06-01), Dower et al.
patent: 6261776 (2001-07-01), Pirrung et al.
patent: 6287765 (2001-09-01), Cubicciotti
patent: 6297059 (2001-10-01), Song et al.
patent: 6310191 (2001-10-01), Collins et al.
patent: 6312664 (2001-11-01), Brasch et al.
patent: 6316268 (2001-11-01), Yang et al.
patent: 6316616 (2001-11-01), Jacobsen et al.
patent: 6331441 (2001-12-01), Balch et al.
patent: 6344272 (2002-02-01), Oldenburg et al.
patent: 6346413 (2002-02-01), Fodor et al.
patent: 6346423 (2002-02-01), Schembri
patent: 6361944 (2002-03-01), Mirkin et al.
patent: 6372907 (2002-04-01), Lee et al.
patent: 6410585 (2002-06-01), Larsen et al.
patent: 6419881 (2002-07-01), Weinberg et al.
patent: 6428811 (2002-08-01), West et al.
patent: 6489093 (2002-12-01), Jacobsen et al.
patent: 6528020 (2003-03-01), Dai et al.
patent: 6543936 (2003-04-01), Feldman
patent: 6627396 (2003-09-01), Swanson et al.
patent: 6645517 (2003-11-01), West et al.
patent: 6649356 (2003-11-01), Bryan et al.
patent: 6652835 (2003-11-01), Lauffer et al.
patent: 6667159 (2003-12-01), Walt et al.
patent: 6673533 (2004-01-01), Wohlstadter et al.
patent: 6698201 (2004-03-01), Sarkar et al.
patent: 6699501 (2004-03-01), Neu et al.
patent: 6699719 (2004-03-01), Yamazaki et al.
patent: 6767194 (2004-07-01), Jeon et al.
patent: 6767706 (2004-07-01), Quake et al.
patent: 6844165 (2005-01-01), Hutchens et al.
patent: 6872574 (2005-03-01), Cravatt et al.
patent: 6875620 (2005-04-01), Schembri
patent: 7018792 (2006-03-01), Swanson et al.
patent: 7160734 (2007-01-01), Hutchens et al.
patent: 2002/0019015 (2002-02-01), Lahiri et al.
patent: 2002/0090728 (2002-07-01), Shair et al.
patent: 2002/0187197 (2002-12-01), Caruso et al.
patent: 2002/0187347 (2002-12-01), Halas et al.
patent: 2002/0187509 (2002-12-01), Shao et al.
patent: 2003/0083235 (2003-05-01), Danishefsky et al.
patent: 2003/0104360 (2003-06-01), Still et al.
patent: 2003/0138853 (2003-07-01), Lahiri et al.
patent: 2003/0143756 (2003-07-01), Fisher et al.
patent: 2003/0156991 (2003-08-01), Halas et al.
patent: 2003/0175517 (2003-09-01), Voigt et al.
patent: 2003/0219384 (2003-11-01), Donath et al.
patent: 2003/0228605 (2003-12-01), Slootstra et al.
patent: 2004/0010126 (2004-01-01), Lubman et al.
patent: 2004/0013721 (2004-01-01), Antipov et al.
patent: 2004/0076681 (2004-04-01), Dennis et al.
patent: 2004/0077102 (2004-04-01), Coute et al.
patent: 2004/0102607 (2004-05-01), Danishefsky et al.
patent: 2004/0137526 (2004-07-01), Hanash et al.
patent: 2004/0151733 (2004-08-01), Livingston et al.
patent: 2004/0185473 (2004-09-01), Cuppoletti et al.
patent: 2004/0203049 (2004-10-01), Schembri
patent: 2004/0208884 (2004-10-01), Danishefsky et al.
patent: 2006/0051802 (2006-03-01), Carlson
patent: 197 40 263 (1998-05-01), None
patent: 0482727 (1992-04-01), None
patent: 1143252 (2001-10-01), None
patent: 1310794 (2003-05-01), None
patent: 2 319 838 (1998-06-01), None
patent: WO 93/25910 (1993-12-01), None
patent: WO 95/02566 (1995-01-01), None
patent: WO 98/12156 (1998-03-01), None
patent: WO 99/25384 (1999-05-01), None
patent: WO 00/13016 (2000-03-01), None
patent: WO 00/13017 (2000-03-01), None
patent: WO 00/16733 (2000-03-01), None
patent: WO 00/66790 (2000-11-01), None
patent: WO 00/79008 (2000-12-01), None
patent: WO 01/01140 (2001-01-01), None
patent: WO 01/02839 (2001-01-01), None
patent: WO 01/18545 (2001-03-01), None
patent: WO 01/46698 (2001-06-01), None
patent: WO 02/42775 (2002-05-01), None
patent: WO 03/012390 (2003-02-01), None
patent: WO 03/031975 (2003-04-01), None
patent: WO 03/033674 (2003-04-01), None
patent: WO 03/043684 (2003-05-01), None
patent: WO 03/074990 (2003-09-01), None
patent: WO 2004/011476 (2004-02-01), None
patent: WO 2006/017180 (2006-02-01), None
patent: WO 2006/061207 (2006-06-01), None
International Search Report and Written Opinion mailed May 15, 2009.
U.S. Appl. No. 10/703,779 Office Action dated Aug. 5, 2009.
U.S. Appl. No. 10/703,876 Office Action dated Jul. 23, 2009.
U.S. Appl. No. 10/706,573 Office Action dated Sep. 2, 2009.
U.S. Appl. No. 10/813,568 Office Action dated Jul. 22, 2009.
U.S. Appl. No. 10/813,612 Office Action dated Jul. 8, 2009.
U.S. Appl. No. 10/934,977 Office Action dated Aug. 21, 2009.
U.S. Appl. No. 11/004,593 Office Action dated Sep. 15, 2009.
U.S. Appl. No. 11/217,384 Office Action dated Aug. 17, 2009.
U.S. Appl. No. 11/219,338 Office Action dated Dec. 28, 2009.
“Introducing Human Cancer OligoArray™”, Sigma Genosys, 1 page (2002).
Various Search Reports, 109 pages (2001-2002).
Buchanan, J. et al., “Practical synthesis of fully-substituted peptide thiazoles,” Tetrahedron Letters, vol. 40, pp. 3985-3988 (1999).
International Search Report dated Feb. 9, 2006.
Grabar, K. et al., “Two-Dimensional Arrays of Colloidal Gold Particles: A Flexible Approach to Macroscopic Metal Surfaces”, Langmuir, 12:2353-2361 (1996).
Morgenthaler, S. et al., “Surfaces with a Hydrophobicity Gradient: Possible Applications in Biological Testing”, European Cells and Materials, 6(1):69 (2001).
Naffin, J. et al., “Immobilized Peptides as High-Affinity Capture Agents for Self-Associating Proteins”, Chemistry & Biology, 10:251-259 (2003).
Reid et al., “Conformationally Constrained Macrocycles that Mimic Tripeptide b-Strands in Water and Aprotic Solvents,” J. Am. Chem. Soc., vol. 124, pp. 5673-5683 (May 22, 2002).
Ruardy, T.

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