Combinatorial 1,4-benzodiazepin-2,5-dione library

Details Combinatorial 1,4-benzodiazepin-2,5-dione library Combinatorial 1,4-benzodiazepin-2,5-dione library

1997-12-23

1999-10-05

Achutamurthy, Ponnathapura

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

540496, 540506, G01N 33543, C07D48704, C07D24324

Patent

active

059623373

ABSTRACT:
A method has now been found of synthesizing a combinatorial library of 1,4-benzodiazepin-2,5-diones on solid supports via an aza-Wittig ring closure, said compounds optionally encoded with tags, and to the use of this library in assays to discover biologically active compounds, and, optionally, to cleave 1,4-benzodiazepin-2,5-diones therefrom.

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