Combinations of selective alpha-adrenergic agonists and antagoni

Details Combinations of selective alpha-adrenergic agonists and antagoni Combinations of selective alpha-adrenergic agonists and antagoni

1989-05-22

1991-06-04

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514212, A61K 3155

Patent

active

050214101

ABSTRACT:
Methods and pharmaceutical formulations of alpha.sub.2 agonists and alpha.sub.3 antagonists which are useful in lowering intraocular pressure (IOP) and treatment of intraocular hypertension. Co-administration of a therapeutic amount of alpha.sub.2 agonist with a potentiating amount of alpha.sub.3 agonist is effective in lowering IOP and treatment of intraocular hypertension.

REFERENCES:
patent: 4496558 (1985-01-01), Demarinis et al.
Chem. Abst. 104:45623n (1986), Van Pinxteren.

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