Combinations of retinoids and minoxidil-type compounds for hair

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514725, 514880, A61K 31505, A61K 3107

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active

051838176

ABSTRACT:
Increase in the rate of hair growth, stimulation of hair follicles to produce new hair growth, prolongation of the anagen phase of the hair cycle, conversion of vellus hair to growth as terminal hair, and treatment of alopecias due to organic dysfunction of the hair follicle is attained in mammalian skins by either oral administration or by topical application to the skin, hair and/or hair follicles of the mammal of effective amounts of a retinoid, particularly retinoic acid, and a minoxidil-type compound. The combination may be administered or applied alone or with other adjunctive compounds including vitamins, such as Vitamin D.sub.3, hormones, and/or antiandrogens.

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Merck Index 9th edition, 1979, pp. 1060, 1287 to 1289.

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