Combination vaccine for swine dysentery and method of use

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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A61K 3902

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042039681

ABSTRACT:
A combination vaccine for increasing the resistance of swine to dysentery infection comprises killed cells of a virulent isolate of Treponema hyodysenteriae in combination with concentrated killed cells of Bacteroides vulgatus, or Fusobacterium necrophorum, or mixtures thereof. This combination vaccine can be adapted for either oral or parenteral administration. For parenteral administration preferably only Bacteroides vulgatus is used in combination with Treponema hyodysenteriae. The oral vaccine is enteric-coated.

REFERENCES:
patent: 4152413 (1979-05-01), Goodnow
patent: 4152414 (1979-05-01), Harris et al.
patent: 4152415 (1979-05-01), Harris et al.
Hudson, M. J. et al., Res. Vet. Sci. 1976 21(3), 366-367, "Swine Dysentery, Protection of Pigs by Oral and Parentoral Immunization with Attenuated Treponema hyodysenteriae".
Harris, D. L. et al., J. Am. Vet. Med. Assoc. 172(4), 468-471, Feb. 1978, "Swine Dysentery, Studies of Onotobiotic Pigs Inoculated with Treponema hyodysenteriae, Bacteroides vulgatus, and Fusobacterium Necrophorum".

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