Combination therapy using signal transduction inhibitors with pa

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 8, 514255, 514383, 514396, 514399, 514449, A61K 3141, A61K 31415, A61K 31335

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active

055654789

ABSTRACT:
The present invention provides compositions and methods for the treatment of cancer in a subject wherein compounds of formula I defined herein in combination with paclitaxel or other modified taxane analogs provide enhanced anticancer effects over the effects achieved with the individual compounds.

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