Combination therapy of respiratory diseases using antibodies...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S130100, C424S133100, C424S135100, C424S141100, C424S147100, C424S164100, C424S178100

Reexamination Certificate

active

09848377

ABSTRACT:
Therapeutically effective anti-viral compositions, useful especially against respiratory diseases caused or mediated by respiratory syncytial virus (RSV) are disclosed, wherein said compositions comprise at least one anti-RSV antibody, including high affinity antibodies, and an additional anti-inflammatory agent, especially corticosteroids, as well as anti-inflammatory antibodies, especially anti-interleukin-6. Also disclosed are methods of using such compositions to treat and/or prevent respiratory diseases. Such compositions may optionally contain other non-antibody anti-viral agents.

REFERENCES:
patent: 5290540 (1994-03-01), Prince et al.
patent: 5824307 (1998-10-01), Johnson
patent: WO 01/82966 (2001-11-01), None
Johnson et al., The Journal of infectious Diseases, 180: 35-40, 1999.
Smyth et al., Immunological responses to respiratory syncytial virus infection in infancy Arch Dis Child 1997 76: 210-214.
Prince, G.A., “Respiratory Syncytial Virus Antiviral Agents”, Expert Opinion on Therapeutic Patents, pp. 753-762, 9/6 (1999).
Ottolini, M.G., et al., “Prevention and Treatment Recommendations for Respiratory Syncytial Virus Infection Background and Clinical Experience 40 years after Discovery,” in Drugs, 54/6, pp. 867-884, (1997).
Jiang, Zili, et al., “Autocrine Regulation and Experimental Modulation of Interleukin-6 Expression by Human Pulmonary Epithelial Cells Infected with Respiratory Syncytial Virus”, Journal of Virology, vol. 72, No. 3, Mar. 1998, pp. 2496-2499.
Prince, Gregory, et al., “Treatment of Respiratory Syncytial Virus Bronchiolitis and Pneumonia in a Cotton Rat Model with Systemically Administered Monoclonal Antibody (Palivizumab) and Glucocorticosteroid”, Journal of Infectious Diseases, vol. 182, No. 5, Nov. 2000, pp. 1326-1330.
Bulow et al., Prednisolone treatment of Respiratory Syncytial Virus Infection: a randomized controlled trial of 147 infants,Pediatrics, 104 (Dec. 6, 1999), p. e77).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Combination therapy of respiratory diseases using antibodies... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Combination therapy of respiratory diseases using antibodies..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Combination therapy of respiratory diseases using antibodies... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3803019

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.