Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1990-07-24
1991-11-19
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
530351, A61K 3702
Patent
active
050664891
ABSTRACT:
Therapeutic treatment of malignant melanoma in humans is disclosed wherein a synergistically effective amount of DTIC in combination with IL-2 is administered to an individual having such cancer.
REFERENCES:
patent: 4518584 (1985-05-01), Mark et al.
patent: 4604377 (1986-08-01), Fernandes et al.
patent: 4690915 (1987-09-01), Rosenberg
patent: 4766106 (1988-08-01), Katre et al.
Comis, Cancer Treatment Reports, vol. 60, No. 2, 1976.
Dorr et al., Cancer Chemotherapy Handbook, pp. 362-367, 1980, by Elsevier North Holland, Inc. Third Printing (1981).
Roth et al. Current Concepts of Oncology vol. 9(5): 2-11.
Rosenberg et al., The New England Journal of Medicine vol. 316(15): 899-897 (1987).
Salup et al., Cancer Research vol. 46:3358-3363 (1986).
DeVita et al., Cancer Principles & Practice of Oncology 2nd Edition J. B. Lippincott Company (1985) pp. 1405-1408.
Creagan et al., Cancer Treatment Rep vol. 70(5):619-624 (1986).
Roth et al., J Immunol vol. 130:303-308 (1983).
Mule et al., Science vol. 225:1487-1489 (1984).
Cancer Rates and Risks 3rd Edition (1985) NIH Publishing No. 85-691:99-101.
Thurman et al., J. Biol. Resp. Modifiers 5:85-107 (1986).
Legha, Seminars in Oncology 16(1):34-44 (1989).
Stoter et al., Eur J. Cancer Clin. Oncol 25:Supp3 pp. 541-44 (1989).
Shiloni et al., Eur J. Cancer Clin. Oncol. 25:Supp3 pp. 545-549 (1989).
Doyle et al., J. Biol. Response Modifiers 4:96-109 (1985).
Bradley Edward C.
Paradise Carolyn M.
Cetus Corporation
McGarrigle Philip L.
Murphy Lisabeth F.
Schain Howard E.
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