Combination therapy for treating protein deficiencies

Details Combination therapy for treating protein deficiencies Combination therapy for treating protein deficiencies

2004-02-17

2008-11-04

Schnizer, Richard (Department: 1635)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S315000, C514S277000, C514S025000, C435S208000

Reexamination Certificate

active

07446098

ABSTRACT:
This application provides methods of improving gene therapy by combining gene therapy with active site-specific chaperones (ASSCs). The ASSC increases the stability and efficiency of the protein encoded by the recombinant gene that is administered.

REFERENCES:
patent: 6051598 (2000-04-01), Shayman et al.
patent: 6066626 (2000-05-01), Yew et al.
patent: 6200812 (2001-03-01), Pati et al.
patent: 6255113 (2001-07-01), Zarling et al.
patent: 6274597 (2001-08-01), Fan et al.
patent: 6589964 (2003-07-01), Fan et al.
patent: 6599919 (2003-07-01), Fan et al.
patent: 6774135 (2004-08-01), Fan et al.
patent: 2002/0035072 (2002-03-01), Fan et al.
patent: 2004/0204379 (2004-10-01), Cheng et al.
Verma et al (Nature 389:239-242, 1997) □□.
Anderson (Nature 392:25-30, 1998) □□.
Romano et al (Stem Cells 18: 19-39, 2000) □□.
Somia and Verma (Nature Reviews Genetics 1: 91-99, 2000).
Rosenfeld and Collins (Chest 109:241-252, 1996).
Rosenecker (Eur. J. Med. 23(3): 149-156, Mar. 1998).
Boucher (TIG 1.2(3): 81-84, 1996, p. 81, paragraph bridging columns 2 and 3).
Alton and Geddes (J. R. Soc. Med 90 Suppl 31: 43-46 1997).
Davies (Mol. Med Today 4(7): 292-299, Jul. 1998, pp. 294, col. 2, lines 20-28).
Boucher (J. Clin. Invest. 103(4): 441-445 Feb. 1999).
Wilson (J. Clin. Invest. 96: 2547-2554, 1995).
Ferrari et al (Adv. Drug Del. Rev 54:1373-1393, 2002).
Fan (Trends in Pharm. Sci. 24(7): 355-360, 2003).
Hendricks et al (Blood 96 (11 part 1): 845a, 2000).
Handa et al (Dermatology 200: 262-265, 2000).
Handa et al., 2000, “A case of symptomatic heterozygous female Fabry's disease without detectable mutation in the alpha-galactosidase gene,” Dermatology 200:262-265.

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