Combination therapy for the treatment of diabetes and obesity

Details Combination therapy for the treatment of diabetes and obesity Combination therapy for the treatment of diabetes and obesity

1997-10-30

1999-06-01

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530324, 530350, 514312, 424309, A61K 3800, A61K 3124, C07K 500, C07K 1600

Patent

active

059088303

ABSTRACT:
The combination of a metabolic rate modifying agent (e.g., a .beta..sub.3 adrenergic receptor agonist) and a feeding behavior modifying agent (e.g., a NPY5 antagonist) is useful in the treatment of obesity and diabetes, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients. Methods of treating obesity and diabetes are also described.

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De Vos et al, J. Biol Chem, vol. 270. No. 27, Jul. 7, pp. 15958-15961.

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