Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-07-21
1996-11-26
Travers, Russell
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514400, A61K 31495
Patent
active
055785972
ABSTRACT:
The combination of the HIV protease inhibitor L-735,524 and one of ketoconazole or cimetidine is useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
REFERENCES:
Brockmeyer et al 1988, Clinical Immunol Immunopathol vol. 48(1) pp. 50-60-Med Abstract-AIDSline Document#: Med-88253871.
Deutsch Paul J.
Nies Alan
Spector Reynold
Merck & Co. , Inc.
Meredith Roy D.
Travers Russell
Tribble Jack L.
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