Combination therapy for advanced cancer

Details Combination therapy for advanced cancer Combination therapy for advanced cancer

1996-08-22

1998-10-20

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Heavy metal or compound thereof

514183, A61K 3133, A61K 3324

Patent

active

058243461

ABSTRACT:
There is disclosed a method for treating advanced cancer in patients in need of such treating. Temozolomide and cisplatin are administered in combination in amounts sufficient to achieve a clinical response.

REFERENCES:
Piccioni et al., J. Chemother (Florence) (1995) 7(3) pp. 224-229 (Abstract only) Reference to Follow in Due Course.
Buziad, et al., Drug News and Perspectives (DN&P) 8 (8) pp. 480-485 (Oct., 1995.).
Anderson, et al., Oncology 9 (11) p. 1149ff. (Nov., 1995).
Pera, et al., Br. J. Cancer, 71 (5), pp. 904-906 (1995).
Bleehen, et al., Journal of Clinical Oncology, 13 (4), pp. 910-913 (Apr., 1995).
Newlands, Br. J. Cancer 65 (2), 287-291 (1992).
Rosenberg, et al., Nature 205 pp. 698-699 (1995).
Rosenberg, et al., Nature 222 pp. 385-386 (1972).
Piccioni, et al.; Cisplatin Increases Sensitivity of Human Luekiemic Blasts to Triazene Compounds; J. of Chemotherapy, vol. 7 -n. 3 (224-228) 1995.

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