Combination preparation having antithrombotic action

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ortho-hydroxybenzoic acid or derivative doai

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Details

514573, 514739, 514822, A61K 3119, A61K 31045, A61K 3160

Patent

active

050933256

ABSTRACT:
The invention relates to a combination preparation for thrombosis treatment consisting of acetylsalicylic acid and carbacyclin derivatives.

REFERENCES:
S. Stuerzebecher et al., "Platelet Inhibitory and Hemodynamic Effects of a New Stable PGl.sub.2 Analogue, Cicaprost (ZK 96480), in Different Animal Species and in Man," Biomed. Biochim. Acta 47 (1988), 10/11, S45-S47.
Merck Index, Tenth Edition, p. 123, Aspirin.
Prostaglandins 36(6): 751-760, 1988, Stuerzebecher & Witt, The PGI.sub.2 -analog Iloprost and the TXA.sub.2 -receptor Antagonist Sulotroban Synergistically Inhibit TXAZ-dependent Platelet Activation.
Biomed. Biochim. Acta 47(10-11): 545-547, 1989, Stuerzebecher, Hildebrand, Schoebe, Seifert & Staks, Platelet Inhibitory and Hemodynamic Effects of a New Stable DGI.sub.2 Analog, Cicaprost (ZK96480), in different animal species & man.

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