Combination preparation for stimulating the growth of hair and o

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424450, 424401, A61K 948

Patent

active

060132795

DESCRIPTION:

BRIEF SUMMARY
The invention relates to a combination preparation for stimulating, on the one hand, the growth of hair and, optionally, the growth of skin and nails and for preventing or eliminating, on the other hand, the loss of hair to the extent that the hair follicles are still present or intact. More specifically, the combination preparation is a combination of active ingredients which contains vitamins, enzymes, and amino acids.
In practice, preparations for stimulating the growth of hair have been known for a long time, and they comprise a great variety of compositions. For example, such preparations may contain sulfur or sulfur compounds, vitamins, hormones, cholesterol- and lecithin-containing substances. On the one hand, such combination preparations are used for the preventive preservation and the health of the hair. On the other hand, however, they are also used for curing the loss of hair.
In both women and men, the occurrence of an increased loss of hair is accompanied by the fear of becoming totally bald-headed. Besides the medical aspect, disturbances in the hair growth thus present a great personal problem for the affected person. The rate of growth of the hair amounts to about 0.35 mm per day, the hair density is from about 80,000 to 150,000 hairs per head. A loss of 100 hairs per day constitutes already a pathological effluvium.
From hair follicles that remained intact, hair are able to regrow. However, during a multiphase, lengthy regrowth, hair follicles may shrink and lead to a gradual loss of hair.
For some years, Applicant has had on the market a GKL complex, whose combination of active ingredients is enriched with a high percentage of amino acids, enzymes, and vitamins B, E, and F. In particular, the known combination preparation contains an extract from calf thymus, vegetable extracts, and animal oils. The GKL complex of active ingredients has successfully been tested in numerous clinics and institutes by treating different forms of alopecia. One of the numerous publications appeared, for example, in the medical journal "Der Onkologe" (1/90), or in the special print of the medical journal "Der Deutsche Dermatologe" (11/93).
As a whole, is has resulted from several tests that the GKL complex of active ingredients is effective for all kinds of hair loss in men and women, that it prevents androgenic hair loss, avoids development of baldness and hair loss in cancer patients undergoing light to moderate chemotherapy and, moreover, that it also counteracts the development of dandruff.
The use of known hair growth stimulants in general and the GKL complex of active ingredients in particular is normally external. The forms of application of the known hair stimulants media are liquid. The flowable products are offered in the form of emulsions, lotions, shampoos, hair cures or hair tonics.
Also known are, when viewed alone, nutritional supplements, which serve to favorably influence the metabolism of the human body, and facilitate achieving purposeful effects. Nutritional supplements, which are directed to a dietetic use, are capable of effecting, for example, as a result of their composition, a protection against oxidation by bonding free radicals which develop to an increasing extent just in the case of a diet. The nutritional supplements become active within the body, in particular by resorption of endogenous cells.
Based on these interrelated topics, which are per se totally different, but form a complex of topics, it is the object of the present invention to describe a combination preparation of the kind under discussion, which spreads its effect from within the body into the body cells. To enhance the effectiveness of the combination preparation under discussion, at least with respect to stimulating the hair growth, a use of the combination preparation will also be described.
The combination preparation of the present invention is formulated such that its combination of active ingredients is a component of a form of administration for oral or even topical use, and that the combination of ingredient

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