Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1994-12-02
1998-12-01
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514492, 514651, 424649, A61K 31135, A61K 3128, A61K 3324
Patent
active
058440011
ABSTRACT:
The present invention provides a composition of matter for the treatment of non-melanoma cancers, wherein said composition comprises a platinum anti-neoplastic compound and tamoxifen, wherein said platinum anti-neoplastic compound and tamoxifen exert a synergistic anti-tumor effect on said non-melanoma cancer. Also provided are various methods of treating non-melanoma cancers and methods of preventing or overcoming resistance to platinum-containing anti-neoplastic compounds.
REFERENCES:
patent: 5578590 (1996-11-01), Grunicke et al.
Scambia et al, Eur. J. Cancer, vol. 28A, No. 11, pp. 1885-1889 (Sep. 9, 1992.
The Merck Index, 11th Ed, Merck & Co, Inc. Rahway, N.J. 1989, p. 276 (no 1828).
Howell Stephen B.
Los Gerrit
McClay Edward F.
Adler Benjamin Aaron
Goldberg Jerome D.
Research Development Foundation
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