Combination particles for the treatment of asthma

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

Reexamination Certificate

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Details

C424S045000, C424S489000, C514S171000, C514S174000, C514S826000

Reexamination Certificate

active

10398381

ABSTRACT:
Inhalation particles incorporating, in an individual particle, a combination of a βhd 2-agonist and a glucocorticosteroid in a predetermined and constant ratio, a process for the preparation thereof and pharmaceutical compositions comprising the inhalation particles. The particles have a narrow particle size distribution and are preferably in the form of spherical crystalline particles with a rough surface. The particles are particularly useful in the treatment of asthma and other respiratory disorders.

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D. Bouros et al., “Formoterol and beclomethasone versus higher dose beclomethasone as maintenance therapy in adult asthma,” Eur Respir J, vol. 14, pp. 627-632, 1999.

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