Combination of two or more drugs in a single dosage form wherein

Details Combination of two or more drugs in a single dosage form wherein Combination of two or more drugs in a single dosage form wherein

1980-05-01

1981-07-14

Cacciapaglia, Frank

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424274, 424244, 424265, 424267, 424278, 424330, A61K 3144, A61K 3140, A61K 3133, A61K 3146

Patent

active

042786797

ABSTRACT:
This invention relates to the combination of a physostigmine compound, including physostigmine, physostigmine salicylate, physostigmine sulfite, physostigmine sulfate and other esters and salts of physostigmine, in single dosage form, with one or more drugs that produce anticholinergia as an undesirable side effect, so that the physostigmine compound offsets the undesirable side effects, and makes a known drug or drugs, to which a physostigmine compound is added, safer and more desirable for patients to take. Physostigmine is also known as eserine.

REFERENCES:
Rumack, Pediatrics, 52:3, (9/73), "Anticholinergic Poisoning: Treatment with Physostigmine," (3 pp.).
Manoguerra et al., J. Am. Col. of Emergency Physicians & Univ. Assoc. for Medical Emergency Services, 5:2, (2/76), pp. 125-127.
Walker et al., J. Am. Col. of Emergency Physicians & Univ. Assoc. for Medical Emergency Services, 5:6, (6/76), pp. 436-439.
Johnson, J. Am Col. of Emergency Physicians & Univ. Assoc. for Medical Emergency Services, 5:6, (6/76), pp. 443-445.
Smiler et al., Am. J. Obs. Gyn, 116:3, pp. 326-329, (1973).
Smith et al., J. Int'l Anesthesia Res. Soc., 55:4, (7/8-76), pp. 478-480.

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