Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-03-09
1993-07-13
Friedman, S. J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61K 3155
Patent
active
052273784
ABSTRACT:
The invention relates to compositions comprising combinations of a PAF antagonist and a LTD.sub.4 antagonist which combinations synergistically provide protection against allergic reactions such as antigen-induced death in mammals.
In another aspect, the invention relates to the use of the referred to combinations in the treatment of allergic reactions.
REFERENCES:
O'Donnell et al., Proceedings of the Fourth International Conference of the Inflammation Research Association held Oct. 23-27, 1988; Elsevier (Publisher), New York, Published Aug. 22, 1989.
Patterson et al., Int. Arch. Allergy Appl. Immunol., 88: 462-470 (1989).
O'Donnell Margaret
Welton Ann
Friedman S. J.
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
Krovatin William
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