Combination of loteprednol and antihistamines

Details Combination of loteprednol and antihistamines Combination of loteprednol and antihistamines

2006-04-04

2006-04-04

Cook, Rebecca (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C514S217050, C514S330000

Reexamination Certificate

active

07022687

ABSTRACT:
The present invention relates to a novel combination of a soft steroid, in particular loteprednol, and at least one antihistamine, such as, for example, azelastine and/or levocabastine, for simultaneous, sequential or separate administration in the local treatment of allergies and airway disorders, for example of allergic rhinitis (rhinoconjunctivitis).

REFERENCES:
patent: 4710495 (1987-12-01), Bodor
patent: 4996335 (1991-02-01), Bodor
patent: 0 709 099 (1996-05-01), None
patent: WO 97/01337 (1997-01-01), None
Friedlaender, Current Opinion in Ophthalmology 1998, 9/4 54-58.
Isaac, Lancet, Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema, vol. 351, pp. 1225-1332, Aug. 25, 1998.
I. Annesi-Maesano et al., Revue Francaise d'Allergologie, “La rhinite de l'adolescent Resultats de l'enquete ISAAG” vol. 38, pp. 283-289, 1998.
Medline, E. Norman et al., European Journal of Allergy, “Prevalence and incidence of asthma and rhinoconjunctivitis in Swedish teenagers,” vol. 53, pp. 28-35, 1998, abstract.

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