Combination of flupirtine and tramadol

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S650000

Reexamination Certificate

active

07553858

ABSTRACT:
The subject of the present invention is to provide a combination of two centrally acting analgesics, flupirtine and tramadol, or their respective pharmaceutically acceptable salts for the treament of pain.

REFERENCES:
patent: 2314746 (2001-02-01), None
Grond et al. High-dose tramadol in comparison to low-dose mrophine for cancer pain relief. Journal of Pain and Symptom Management. vol. 18, No. 3 Sep. 1999. pp. 174-179.
Friedel et al. Flupirtine A review of its pharmacological properties, and therapeutic efficacy in pain states. Drug Evaluation, Drugs 45 (4): pp. 548-569, 1993.

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