Combination of .beta.-adrenoceptor antagonists and anxiolytic ag

Details Combination of .beta.-adrenoceptor antagonists and anxiolytic ag Combination of .beta.-adrenoceptor antagonists and anxiolytic ag

1982-06-25

1984-08-28

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3133

Patent

active

044683910

ABSTRACT:
A .beta.-adrenoceptor antagonist, which does not penetrate or penetrates poorly the brain, is combined with subtherapeutic doses of an anxiolytic agent, such as diazepam, to give a method, and pharmaceutical or veterinary composition, for treating anxiety, stress or aggressivity without deleterious side effects associated with the central nervous system.

REFERENCES:
patent: 3959486 (1976-05-01), LeCount et al.
patent: 4059622 (1977-11-01), LeCount et al.
patent: 4190654 (1980-02-01), Gherardi et al.
Z. Rolinski and W. Kozak, Pol. J. Pharmacol. Pharm., 32, 731, (1980).
C. Hallstrom et al., Brit. J. Psychiat., 139, 417, (1981).

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