Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-02-15
2005-02-15
Cook, Rebecca (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S267000
Reexamination Certificate
active
06855712
ABSTRACT:
The use of a protecting agent, for example a folate derivative such as folic acid or leucovorin, in combination with a non-competitive folic acid analogue, for example benzoquinazoline derivatives, for use in reducing the side effects associated with the administration of such non-competitive folic acid analogues, and pharmaceutical formulations comprising such combinations are disclosed.
REFERENCES:
patent: 5661155 (1997-08-01), Pendergast et al.
patent: 6306865 (2001-10-01), Pendergast et al.
patent: 6358952 (2002-03-01), Smith et al.
patent: 6579877 (2003-06-01), Smith et al.
Duch David Stanley
Ferone Robert
Koch Arthur
Smith Gary Keith
Cook Rebecca
Lemanowicz John L.
SmithKline Beecham Corporation
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