Surgery – Radioactive substance applied to body for therapy – Radioactive substance placed within body
Reexamination Certificate
2006-05-09
2006-05-09
Hook, James (Department: 3754)
Surgery
Radioactive substance applied to body for therapy
Radioactive substance placed within body
C600S004000, C600S007000
Reexamination Certificate
active
07041046
ABSTRACT:
The present invention provides improved devices, methods, and kits for inhibiting restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides controlled immunomodulator delivery in combination with ionizing radiation to selected locations within a patient's vasculature to reduce and/or inhibit restenosis and hyperplasia rates with increased efficacy. In one embodiment, the combination radiation and immunomodulator delivery catheter for inhibiting hyperplasia comprises a catheter body having a proximal end and distal end, an ionizing radiation source coupleable to the catheter body for applying a radiation dose to a body lumen, and a porous material, matrix, membrane, barrier, coating, infusion lumen, stent, graft, or reservoir for releasing an immunomodulator to the body lumen.
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Fruburger Thomas M.
Hook James
Xoft, Inc.
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