Combination gene therapy for human cancers

Details Combination gene therapy for human cancers Combination gene therapy for human cancers

1997-10-23

2000-02-29

Campbell, Bruce R

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 232, 536 235, 536 241, 4284022, 4353201, C12N 1500, A01N 4304, C07H 2104, B32B 516

Patent

active

060309563

ABSTRACT:
A method of treating cancer in a subject, by administering to the subject a combination of genes including wt p53, Pax5 and HSV-tk genes is disclosed. The method may involve subsequently treating the subject with ganciclovir.

REFERENCES:
Kwong et al. Cancer Gene Therapy 3(5) 339-44, Sep. 1996.
Mujoo et al. Oncogene 12(8) 1617-23, Apr. 1996.
Roth et al. Nature Medicine 2(9) 985-91, Sep. 1996.
Mastrangelo et al. Seminars in Oncology, vol. 23 (1) 4-21, Feb. 1996.
Orkin et al. Report and recommedation of the panel to assess the NIH investment in research on gene therapy, Dec. 1995.

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